The small Caenorhabditis elegans roundworm was looked at very closely by researchers studying a crucial aspect of biochemistry in living beings. Their recent results reveal that they somehow tend to live longer when these nematodes are placed under more oxidative pressure early in their lives.
This form of stress called oxidative stress— and excess in oxygen-containing molecules that can cause harm to the cells and tissues — seems to better prepare the worms for the stresses of later life, along the same lines as the adage that anything that doesn’t destroy you makes you stronger.
You may assume that the lifetime of the worm has no impact on human survival. So obviously, it would be a huge stretch to claim the same ideals of prolonging one’s lifetime could apply to human beings until we have tons of more research done in this area.
However, there is a good reason to put C. Via paces, elegant. This model organism has revealed incredibly helpful for scientists seeking to better understand crucial biological functions found in both worms and humans-and one such function is oxidative stress.
Even when the entire population is genetically similar and evolves under precisely the same environments, the little wriggly animals are recognised to have major differences in their lifetime.
The researchers found other influences that had an impact on C. Longevity of elegance.
“The basic idea that experiences in early years have such significant, positive effects in life, later on, is truly fascinating,” states University of Michigan biochemist Ursula Jakob.
Jakob processed thousands of C for her coworkers. Elegans larvae depend on the levels of oxidative stress they encountered during their growth–this stress happens when cells create further oxidants and free radicals than they can accommodate. It is a necessary part of the process of ageing, but it is also triggered by exercise and a limited supply of food.
There are still a lot of unanswered questions to address, but the experts believe their reports describe one of the stochastic–or spontaneous –effects on organisms ‘ lifespan; it’s something that has been speculated in the ageing genetics sector. And down the line, it may also be applicable for elderly people.
“This analysis provides a basis for forthcoming mammalian studies in which very early and intermittent metabolic activities in life tend to have similarly profound effects on lifespan,” the authors conclude.